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임신 중 formamidine sulfinic acid을 피해야 할까요? | VeriMom

Animal reproductive/developmental data in the OECD SIDS report show reduced litter size and effects on corpora lutea at high doses and a NOAEL for reproductive performance of 15 mg/kg bw in rats, so reproductive hazard is suspected (h=2). No harmonised EU CMR Category 1 (H360/H350/H340) is listed for this substance on ECHA; the reproductive effects appear secondary to maternal toxicity rather than a characterised endocrine mechanism, so mechanism is scored as theoretical/demonstrated by animal study (m=1). Dermal/topical exposure is expected to give low but measurable systemic exposure (low logP, water soluble), so exposure score is 1. Sources: OECD SIDS (reproduction data) and ECHA substance record.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

formamidine sulfinic acid은 임신 중 안전한가요?
Animal reproductive/developmental data in the OECD SIDS report show reduced litter size and effects on corpora lutea at high doses and a NOAEL for reproductive performance of 15 mg/kg bw in rats, so reproductive hazard is suspected (h=2). No harmonised EU CMR Category 1 (H360/H350/H340) is listed for this substance on ECHA; the reproductive effects appear secondary to maternal toxicity rather than a characterised endocrine mechanism, so mechanism is scored as theoretical/demonstrated by animal study (m=1). Dermal/topical exposure is expected to give low but measurable systemic exposure (low logP, water soluble), so exposure score is 1. Sources: OECD SIDS (reproduction data) and ECHA substance record.
formamidine sulfinic acid은 모유 수유 중 안전한가요?
No human breastfeeding-specific data were found. Animal reproductive data (OECD SIDS) that indicate effects on reproductive performance support a suspected hazard during lactation (h=2). Mechanistic evidence is limited (m=1). Expected systemic exposure from topical use is low but measurable (e=1); transfer in milk is not documented.
formamidine sulfinic acid은 아기 피부에 안전한가요?
No infant-specific studies were identified. Because animal reproductive/developmental toxicity exists (OECD SIDS), the same suspected hazard rating (h=2) is applied. Mechanistic data remain limited (m=1). Exposure for infants (0–3 yr) is increased by one point relative to adults because immature skin has higher absorption; therefore exposure is e=2 (adult e=1 → baby +1).
VeriMom은 formamidine sulfinic acid을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 formamidine sulfinic acid을 27/100 (높은 위험)로 평가합니다.
임신 중 formamidine sulfinic acid 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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