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임신 중 diisononyl phthalate을 피해야 할까요? | VeriMom

Diisononyl phthalate (DINP) has a harmonised ECHA flag of H361 (suspected of damaging fertility or the unborn child), and animal studies report adverse effects on placental/gestational outcomes and reproductive development in rodents, so reproductive hazard is suspected (h=2). Mechanistic and endocrine-disruption evidence (in vivo rodent effects and reported endocrine activity) supports a demonstrated mechanism (m=2). For typical topical cosmetic use, dermal absorption and systemic exposure are low but measurable (exposure = 1); most human exposure routes reported in regulatory assessments are dietary/consumer products rather than intentional cosmetic use. (Sources: ECHA brief profile/C&L inventory; peer-reviewed rodent studies; EPA risk evaluation).

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

diisononyl phthalate은 임신 중 안전한가요?
Diisononyl phthalate (DINP) has a harmonised ECHA flag of H361 (suspected of damaging fertility or the unborn child), and animal studies report adverse effects on placental/gestational outcomes and reproductive development in rodents, so reproductive hazard is suspected (h=2). Mechanistic and endocrine-disruption evidence (in vivo rodent effects and reported endocrine activity) supports a demonstrated mechanism (m=2). For typical topical cosmetic use, dermal absorption and systemic exposure are low but measurable (exposure = 1); most human exposure routes reported in regulatory assessments are dietary/consumer products rather than intentional cosmetic use. (Sources: ECHA brief profile/C&L inventory; peer-reviewed rodent studies; EPA risk evaluation).
diisononyl phthalate은 모유 수유 중 안전한가요?
Because DINP is flagged H361 and shows reproductive/developmental effects in animal studies, it is treated as a suspected reproductive hazard for lactation contexts (h=2). Mechanistic evidence (endocrine activity and documented developmental effects in animal studies) supports m=2. Exposure from topical cosmetic use by a breastfeeding person is expected to be low but measurable (e=1); available regulatory reviews indicate diet and mouthing/consumer articles are larger exposure sources than cosmetics.
diisononyl phthalate은 아기 피부에 안전한가요?
Hazard (h=2) remains 'suspected' based on the harmonised ECHA classification (H361) and animal developmental/reproductive findings. Mechanistic score is unchanged (m=2). Exposure is increased by +1 for infants (e=2) because (a) DINP is lipophilic and has measurable systemic uptake in toxicology studies and (b) infant skin has higher surface-area-to-weight and an immature barrier; thus dermal exposure from products that contact baby skin would be moderate compared with adults. Note: available sources indicate DINP is primarily used as a PVC/plasticizer and is not commonly listed in CosIng as a cosmetic ingredient, so direct cosmetic-product dermal exposure to infants may be uncommon, but contamination or presence in articles (toys, PVC items) is documented.
VeriMom은 diisononyl phthalate을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 diisononyl phthalate을 20/100 (높은 위험)로 평가합니다.
임신 중 diisononyl phthalate 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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