임신 중 diisononyl phthalate을 피해야 할까요? | VeriMom
Diisononyl phthalate (DINP) has a harmonised ECHA flag of H361 (suspected of damaging fertility or the unborn child), and animal studies report adverse effects on placental/gestational outcomes and reproductive development in rodents, so reproductive hazard is suspected (h=2). Mechanistic and endocrine-disruption evidence (in vivo rodent effects and reported endocrine activity) supports a demonstrated mechanism (m=2). For typical topical cosmetic use, dermal absorption and systemic exposure are low but measurable (exposure = 1); most human exposure routes reported in regulatory assessments are dietary/consumer products rather than intentional cosmetic use. (Sources: ECHA brief profile/C&L inventory; peer-reviewed rodent studies; EPA risk evaluation).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- diisononyl phthalate은 임신 중 안전한가요?
- Diisononyl phthalate (DINP) has a harmonised ECHA flag of H361 (suspected of damaging fertility or the unborn child), and animal studies report adverse effects on placental/gestational outcomes and reproductive development in rodents, so reproductive hazard is suspected (h=2). Mechanistic and endocrine-disruption evidence (in vivo rodent effects and reported endocrine activity) supports a demonstrated mechanism (m=2). For typical topical cosmetic use, dermal absorption and systemic exposure are low but measurable (exposure = 1); most human exposure routes reported in regulatory assessments are dietary/consumer products rather than intentional cosmetic use. (Sources: ECHA brief profile/C&L inventory; peer-reviewed rodent studies; EPA risk evaluation).
- diisononyl phthalate은 모유 수유 중 안전한가요?
- Because DINP is flagged H361 and shows reproductive/developmental effects in animal studies, it is treated as a suspected reproductive hazard for lactation contexts (h=2). Mechanistic evidence (endocrine activity and documented developmental effects in animal studies) supports m=2. Exposure from topical cosmetic use by a breastfeeding person is expected to be low but measurable (e=1); available regulatory reviews indicate diet and mouthing/consumer articles are larger exposure sources than cosmetics.
- diisononyl phthalate은 아기 피부에 안전한가요?
- Hazard (h=2) remains 'suspected' based on the harmonised ECHA classification (H361) and animal developmental/reproductive findings. Mechanistic score is unchanged (m=2). Exposure is increased by +1 for infants (e=2) because (a) DINP is lipophilic and has measurable systemic uptake in toxicology studies and (b) infant skin has higher surface-area-to-weight and an immature barrier; thus dermal exposure from products that contact baby skin would be moderate compared with adults. Note: available sources indicate DINP is primarily used as a PVC/plasticizer and is not commonly listed in CosIng as a cosmetic ingredient, so direct cosmetic-product dermal exposure to infants may be uncommon, but contamination or presence in articles (toys, PVC items) is documented.
- VeriMom은 diisononyl phthalate을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 diisononyl phthalate을 20/100 (높은 위험)로 평가합니다.
- 임신 중 diisononyl phthalate 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.