임신 중 cis-retinoic acid을 피해야 할까요? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

cis-retinoic acid은 임신 중 안전한가요?

13‑cis‑retinoic acid (isotretinoin, CAS 4759‑48‑2) is a well‑established human teratogen when given systemically (oral isotretinoin causes severe, characteristic birth defects) and is regulated as a pregnancy‑contraindicated retinoid; the teratogenic mechanism is well characterized via retinoic‑acid / retinoid receptor signalling. Topical use gives lower systemic exposure than oral dosing but measurable absorption has been reported for topical retinoids and regulatory guidance treats retinoic acid/isotretinoin as a pregnancy risk. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))

cis-retinoic acid은 모유 수유 중 안전한가요?

Oral isotretinoin is contraindicated in breastfeeding because of concern for systemic exposure to the infant; the biological mechanism (retinoid receptor activity) is the same as for pregnancy. For topical cosmetic use, systemic transfer into milk is expected to be low but not zero, so breastfeeding exposure is considered low but not negligible. ([fda.gov](https://www.fda.gov/media/166611/download?utm_source=openai))

cis-retinoic acid은 아기 피부에 안전한가요?

There is no infant‑specific evidence that topical cis‑retinoic acid applied to baby skin produces developmental/teratogenic effects (do not upgrade h/m without direct data). However infant skin has higher absorption (immature barrier and higher surface‑area‑to‑weight), so exposure scoring is increased relative to adults if the ingredient is present or applied directly. Topical retinoids are generally discouraged on young children because of irritancy and potential systemic uptake. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/32643315/?utm_source=openai))

VeriMom은 cis-retinoic acid을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 cis-retinoic acid을 7/100 (높은 위험)로 평가합니다.

임신 중 cis-retinoic acid 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.