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임신 중 basic green 4을 피해야 할까요? | VeriMom

ECHA has a harmonised CLP entry for malachite green (Basic Green 4, CAS 569-64-2) with a reproductive/developmental suspect classification (H361d — 'suspected of damaging the unborn child'), so reproductive hazard is judged as 'suspected'. Animal and in vitro studies report developmental effects and show that the metabolite leucomalachite green (LMG) is present in dam plasma and amniotic fluid, supporting a plausible mechanism (placental exposure). Topical/cosmetic exposure would likely give low but measurable systemic exposure if used, so exposure score is 1. (ECHA Annex/CLP; rat developmental study).

ECHA regulatory hazard statements

  • H361
  • H361D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

basic green 4은 임신 중 안전한가요?
ECHA has a harmonised CLP entry for malachite green (Basic Green 4, CAS 569-64-2) with a reproductive/developmental suspect classification (H361d — 'suspected of damaging the unborn child'), so reproductive hazard is judged as 'suspected'. Animal and in vitro studies report developmental effects and show that the metabolite leucomalachite green (LMG) is present in dam plasma and amniotic fluid, supporting a plausible mechanism (placental exposure). Topical/cosmetic exposure would likely give low but measurable systemic exposure if used, so exposure score is 1. (ECHA Annex/CLP; rat developmental study).
basic green 4은 모유 수유 중 안전한가요?
Harmonised classification for developmental hazard (H361d) and animal data demonstrating maternal systemic exposure and placental/biological transfer (LMG detected in amniotic fluid) indicate suspected risk to the developing offspring; while direct human lactation studies are lacking, demonstrated maternal systemic absorption/metabolism supports a plausible mechanism for transfer into milk. Typical topical cosmetic use would likely give low but measurable maternal exposure (score 1).
basic green 4은 아기 피부에 안전한가요?
Hazard (H361d) and animal developmental/toxicity data justify the same hazard score for infant skin exposure (do not escalate h/m without infant-specific toxicity data). Mechanistic evidence (LMG in maternal plasma/amniotic fluid) supports m=2. Because infant skin has higher absorption/surface-area-to-weight, exposure score is increased by +1 versus adult topical (adult e=1 → infant e=2). Note: the substance is listed as prohibited in EU cosmetic Annex II / disallowed in baby products in multiple lists, reflecting regulatory precaution.
VeriMom은 basic green 4을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 basic green 4을 20/100 (높은 위험)로 평가합니다.
임신 중 basic green 4 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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