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임신 중 aziridine을 피해야 할까요? | VeriMom

Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.

ECHA regulatory hazard statements

  • H350

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

aziridine은 임신 중 안전한가요?
Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.
aziridine은 모유 수유 중 안전한가요?
Same hazard and mechanism rationale as pregnancy (suspected reproductive/teratogenic risk via genotoxic/alkylating activity). No specific human lactation transfer data located, but systemic toxicity and dermal absorption reported in authoritative sources imply measurable maternal exposure and potential for transfer into breastmilk (therefore e=2).
aziridine은 아기 피부에 안전한가요?
Hazard and mechanism as above (h=2, m=2). Because infant skin (0–3 yr) has higher surface-area-to-weight and an immature barrier, exposure score increases by +1 relative to adult topical exposure (adult e=2 → baby e=3). There is no infant-specific toxicokinetic evidence to change hazard or mechanism scores, only exposure.
VeriMom은 aziridine을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 aziridine을 13/100 (높은 위험)로 평가합니다.
임신 중 aziridine 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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의료 면책 조항

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