임신 중 azadirachta indica seed extract을 피해야 할까요? | VeriMom
Harmonised/regulatory and animal data justify a 'suspected' reproductive hazard. ECHA documentation and regulatory discussion identify margosa (Azadirachta indica) kernel/seed extracts with harmonised H361 (suspected of damaging fertility or the unborn child) for specific extracts prepared from kernels with aqueous + organic solvent processing. Multiple animal studies and reviews report antifertility, abortifacient and fetal/developmental effects (neonatal/fetal malformations, reduced fetal weight) associated with neem seed oil/azadirachtin in rodents, and mechanistic data include progesterone reduction and immune-mediated effects. For topical cosmetic use, dermal absorption is expected to be low but not zero, so exposure is scored as low but measurable. (ECHA CLH/Annex VI; animal/peer-reviewed studies).
ECHA regulatory hazard statements
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- azadirachta indica seed extract은 임신 중 안전한가요?
- Harmonised/regulatory and animal data justify a 'suspected' reproductive hazard. ECHA documentation and regulatory discussion identify margosa (Azadirachta indica) kernel/seed extracts with harmonised H361 (suspected of damaging fertility or the unborn child) for specific extracts prepared from kernels with aqueous + organic solvent processing. Multiple animal studies and reviews report antifertility, abortifacient and fetal/developmental effects (neonatal/fetal malformations, reduced fetal weight) associated with neem seed oil/azadirachtin in rodents, and mechanistic data include progesterone reduction and immune-mediated effects. For topical cosmetic use, dermal absorption is expected to be low but not zero, so exposure is scored as low but measurable. (ECHA CLH/Annex VI; animal/peer-reviewed studies).
- azadirachta indica seed extract은 모유 수유 중 안전한가요?
- Same overall hazard/ mechanism as pregnancy: harmonised H361 for certain margosa/kernel extracts and animal evidence for reproductive effects from seed-derived neem preparations make this a suspected hazard for lactating people. There are no robust human lactation transfer data for cosmetic topical use; because systemic absorption from topical use is generally low but possible, exposure is scored low but measurable. Animal data indicate systemic effects after oral dosing of seed/seed-oil preparations (supporting potential for systemic exposure when dose or formulation allows).
- azadirachta indica seed extract은 아기 피부에 안전한가요?
- Hazard and mechanism remain 'suspected' based on the same harmonised/regulatory classification and animal data tied to seed/kernel extracts. Exposure score is increased by +1 for infant skin (0–3 yr) because infant skin barrier/SA:body-weight considerations raise systemic uptake potential for topically applied ingredients that have any measurable absorption in adults; there are no infant-specific dermal toxicokinetic studies for cosmetic seed extracts. Apply caution for products intended for infants if the formulation contains seed/kernel-derived neem extracts.
- VeriMom은 azadirachta indica seed extract을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 azadirachta indica seed extract을 20/100 (높은 위험)로 평가합니다.
- 임신 중 azadirachta indica seed extract 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.