임신 중 aminoguanidine bicarbonate을 피해야 할까요? | VeriMom
Harmonised EU classification for aminoguanidinium hydrogen carbonate (CAS 2582-30-1) lists Reproductive toxicity Category 1B (H360), which indicates presumed human reproductive toxicity (ECHA). Animal/experimental studies with aminoguanidine report fetal developmental effects in rodents (fetal toxicity, growth effects), and aminoguanidine is a biologically active iNOS inhibitor affecting nitric oxide pathways relevant to pregnancy, supporting a demonstrated mechanism. Topical cosmetic exposure would likely give low but measurable systemic exposure for adults (no data showing negligible/permanent non-absorption). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))
ECHA regulatory hazard statements
- •H360
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- aminoguanidine bicarbonate은 임신 중 안전한가요?
- Harmonised EU classification for aminoguanidinium hydrogen carbonate (CAS 2582-30-1) lists Reproductive toxicity Category 1B (H360), which indicates presumed human reproductive toxicity (ECHA). Animal/experimental studies with aminoguanidine report fetal developmental effects in rodents (fetal toxicity, growth effects), and aminoguanidine is a biologically active iNOS inhibitor affecting nitric oxide pathways relevant to pregnancy, supporting a demonstrated mechanism. Topical cosmetic exposure would likely give low but measurable systemic exposure for adults (no data showing negligible/permanent non-absorption). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))
- aminoguanidine bicarbonate은 모유 수유 중 안전한가요?
- Because the substance has an EU harmonised classification as Repr.1B (H360), the hazard score for breastfeeding is aligned with pregnancy (h=3). The mechanism (iNOS inhibition; demonstrated biological activity) supports potential effects on reproductive/offspring endpoints; no specific lactation transfer data were found, so adult topical exposure is assumed to give low but measurable systemic levels absent formulation-specific data. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))
- aminoguanidine bicarbonate은 아기 피부에 안전한가요?
- Harmonised Repr.1B classification (H360) applies irrespective of age; therefore hazard remains h=3 for infant skin contact. Mechanistic evidence (aminoguanidine biological activity) is applicable. Exposure rating is increased by +1 for baby skin because aminoguanidine is a small, water‑soluble molecule with measurable absorption potential; infant skin has higher absorption per weight, so exposure is likely moderate relative to adults in the absence of specific dermal absorption/formulation data. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.018.143?utm_source=openai))
- VeriMom은 aminoguanidine bicarbonate을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 aminoguanidine bicarbonate을 20/100 (높은 위험)로 평가합니다.
- 임신 중 aminoguanidine bicarbonate 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.