임신 중 2,3-epoxypropyltrimoniium chloride을 피해야 할까요? | VeriMom
Harmonised EU CLP classifications list 2,3-epoxypropyltrimethylammonium chloride (glycidyl trimethylammonium chloride, CAS 3033-77-0) with carcinogenic/mutagenic/reprotoxic categories including H350 and H361F (suspected adverse effects on fertility); this legally binding harmonised classification justifies a 'suspected' reproductive hazard (h=2). ECHA/CLP listings and registration dossier indicate mutagenic/carcinogenic/reprotoxic concerns, and animal/experimental literature on quaternary ammonium compounds shows reproductive/endocrine effects supporting a demonstrated mechanism (m=2). For typical topical cosmetic uses absorption is likely low but potentially measurable for a small reactive glycidyl/quaternary ammonium molecule, so exposure for a pregnant adult is scored as low-measurable (e=1).
ECHA regulatory hazard statements
- •H350
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- 2,3-epoxypropyltrimoniium chloride은 임신 중 안전한가요?
- Harmonised EU CLP classifications list 2,3-epoxypropyltrimethylammonium chloride (glycidyl trimethylammonium chloride, CAS 3033-77-0) with carcinogenic/mutagenic/reprotoxic categories including H350 and H361F (suspected adverse effects on fertility); this legally binding harmonised classification justifies a 'suspected' reproductive hazard (h=2). ECHA/CLP listings and registration dossier indicate mutagenic/carcinogenic/reprotoxic concerns, and animal/experimental literature on quaternary ammonium compounds shows reproductive/endocrine effects supporting a demonstrated mechanism (m=2). For typical topical cosmetic uses absorption is likely low but potentially measurable for a small reactive glycidyl/quaternary ammonium molecule, so exposure for a pregnant adult is scored as low-measurable (e=1).
- 2,3-epoxypropyltrimoniium chloride은 모유 수유 중 안전한가요?
- Because the substance carries harmonised H-codes including suspected reproductive toxicity (H361F) and has mechanistic/animal evidence of reproductive/endocrine disruption, it is scored as 'suspected' for breast-feeding (h=2) with demonstrated mechanism evidence from QAC literature (m=2). There are no direct, high-quality human lactation-transfer studies found; expected dermal exposure from cosmetics would be low but measurable (e=1).
- 2,3-epoxypropyltrimoniium chloride은 아기 피부에 안전한가요?
- Hazard remains 'suspected' (h=2) due to the legally harmonised classifications and supporting toxicology; mechanism evidence from quaternary ammonium/glycidyl reactivity supports m=2. Infant skin has higher absorption (immature barrier, higher surface-area-to-weight), so exposure score is increased by +1 versus adult topical use (adult e=1 → baby e=2) even though infant-specific absorption data for this chemical were not found.
- VeriMom은 2,3-epoxypropyltrimoniium chloride을 어떻게 평가하나요?
- VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 2,3-epoxypropyltrimoniium chloride을 20/100 (높은 위험)로 평가합니다.
- 임신 중 2,3-epoxypropyltrimoniium chloride 대체 안전 성분은?
- 유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.
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의료 면책 조항
이 정보는 교육 목적으로만 제공되며 의학적 조언을 구성하지 않습니다. 안전 점수는 공개적으로 이용 가능한 데이터를 기반으로 하며 모든 위험을 반영하지 않을 수 있습니다. 임신 중 또는 수유 중 제품을 사용하기 전에 항상 의료 전문가와 상담하십시오.