Should I Avoid thiabendazole During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H400
- •H410
What to use instead
Pregnancy-safe ingredients that serve a similar function:
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Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to thiabendazole | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is thiabendazole safe during pregnancy?
- Thiabendazole has an EU harmonised classification that includes reproductive toxicity H360 (Category 1B / H360FD in CLP listings), which meets criteria for confirmed reproductive hazard. ECHA/CLP documents and the EU delegated regulation list H360 for thiabendazole, and multiple developmental/reproductive animal studies (rats, mice, rabbits) and JECFA/WHO monographs report fetal and developmental effects at toxic doses, supporting demonstrable mechanism(s) of developmental toxicity and systemic distribution. Sources: ECHA substance/factsheet and EU CLP entry; peer-reviewed developmental studies and JECFA monographs.
- Is thiabendazole safe while breastfeeding?
- Because of the harmonised H360 classification and animal/peer-reviewed data showing systemic absorption and distribution (including to fetal tissues) and developmental effects, thiabendazole is flagged for reproductive/developmental hazard that is relevant to lactation exposure. Human/animal ADME data show rapid absorption and systemic distribution; lactational transfer is plausible though milk-specific data are limited, so exposure to breastfed infants is considered low but measurable from systemic maternal exposure.
- Is thiabendazole safe for baby skin?
- Hazard and mechanism are not increased for infants absent infant‑specific hazard evidence, but the harmonised H360 classification and animal developmental findings indicate a high reproductive/developmental hazard. Dermal/topical exposure on baby skin is assigned a higher exposure score (+1) because infant skin has higher surface-area-to-weight and an immature barrier and thiabendazole has measurable systemic absorption in ADME studies, so topical use could give measurable systemic exposure in infants.
- How does VeriMom score thiabendazole?
- VeriMom scores thiabendazole at 20/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to thiabendazole?
- See our curated list of pregnancy-safe alternatives to thiabendazole based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.