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HIGH RISK

Should I Avoid silybum marianum callus extract During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H361

Products containing silybum marianum callus extract — check your shelf

These products list silybum marianum callus extract on their INCI. If one is in your routine, consider swapping it during pregnancy.

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to silybum marianum callus extract | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

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FAQ

Is silybum marianum callus extract safe during pregnancy?
No harmonised CLP (Annex VI) classification or authoritative SCCS/CIR safety assessment for this specific ingredient was identified. ECHA/PubChem entries include H361/H373 as aggregated notifications (self-notifications), which per instructions do not justify elevated hazard scoring. There is no clear published mechanism or reproductive toxicity data for the callus extract; topical cosmetic use implies low but measurable dermal exposure.
Is silybum marianum callus extract safe while breastfeeding?
No evidence of reproductive or lactation-specific hazard from authoritative sources. Aggregated listings of H361/H373 exist in PubChem/ECHA notifications but are not harmonised classifications. Dermal exposure from cosmetics would be low but measurable; no data to indicate transfer in breastmilk.
Is silybum marianum callus extract safe for baby skin?
No infant-specific hazard or mechanism data located. Because topical exposure to infants can produce higher systemic exposure per body weight (immature barrier and higher surface-area-to-weight), exposure score is increased by +1 relative to adults (adult e=1 → infant e=2). No data found demonstrating increased infant-specific risk.
How does VeriMom score silybum marianum callus extract?
VeriMom scores silybum marianum callus extract at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to silybum marianum callus extract?
See our curated list of pregnancy-safe alternatives to silybum marianum callus extract based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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