임신 중 pregnenolone acetate을 피해야 할까요? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

pregnenolone acetate은 임신 중 안전한가요?

Hazard: animal and mechanistic evidence that pregnenolone and related steroids modulate sex‑steroid signalling and can affect reproductive tissues (peer‑reviewed studies), and multiple supplier SDSs/self‑classifications list H361 (suspected of damaging fertility/unborn child). Mechanism: demonstrated steroid/estrogen receptor modulation and biological activity in animal models (pregnenolone effects on uterine ER expression and developmental effects in embryos). Exposure: topical cosmetic use historically (e.g., 1% creams) and the molecule is lipophilic so low but measurable dermal absorption is plausible for adults. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

pregnenolone acetate은 모유 수유 중 안전한가요?

Hazard & mechanism: because the acetate is converted to pregnenolone (a steroid precursor) and pregnenolone shows endocrine activity in animals, there is potential risk to the nursing infant if significant systemic maternal exposure occurs; mechanism (steroid activity and ability to alter hormone signalling) is demonstrated in animal studies. Exposure: dermal use by nursing mothers would likely give low but measurable maternal systemic exposure (therefore low infant exposure via breastmilk is plausible), but direct data on lactation transfer are lacking. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

pregnenolone acetate은 아기 피부에 안전한가요?

Hazard & mechanism: same concerns as for pregnancy — conversion to an active steroid (pregnenolone) and demonstrated endocrine/reproductive effects in animal models justify a suspected hazard for infants. Exposure: infant (0–3 yr) skin has higher surface‑area‑to‑weight and less mature barrier; therefore dermal exposure potential is increased (+1 exposure score). Direct infant dermal safety data are not available. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

VeriMom은 pregnenolone acetate을 어떻게 평가하나요?

VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 pregnenolone acetate을 20/100 (높은 위험)로 평가합니다.

임신 중 pregnenolone acetate 대체 안전 성분은?

유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.