HIGH RISK
Should I Avoid methyl morpholine oxide During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H361
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".

Avero
100Avero Solid Deodorant

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L'Occitane
100L´Occitane Powder To-mousse Facial Exfoliator

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100Sustain Yourself Natural Deodorant

Bitamin
100Bitamin Natural Deodorant N'orange

Routine
99Routine Sweet Jane Deodorant Jar

Laura Mercier
99Laura Mercier Tinted Moisturizer Broad Spectrum Spf 20 - Oil Free

Routine
99Routine The Curator

bareMinerals
99bareMinerals Complexion Rescue Tinted Hydrating Gel Cream SPF 30
Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to methyl morpholine oxide | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is methyl morpholine oxide safe during pregnancy?
- ECHA lists 4‑methylmorpholine 4‑oxide (N‑methylmorpholine N‑oxide; CAS 7529‑22‑8) with a harmonised CLP reproductive hazard H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). A specific molecular mechanism for reproductive effects is not described in available dossiers, so mechanism is scored as theoretical/uncertain (m=1). For typical topical cosmetic use dermal exposure is low but measurable (hydrophilic substance, low logP), so adult exposure is scored low (e=1). Sources: ECHA classification and supplier/MSDS listings.
- Is methyl morpholine oxide safe while breastfeeding?
- Harmonised H361f (ECHA) applies to general reproductive/fertility concern and is the principal driver (h=2). No clear data on mammary/milk transfer or neonatal toxicity were found; mechanism remains uncharacterized (m=1). Given the compound's hydrophilicity and expected low dermal/systemic absorption from cosmetics, exposure via topical maternal use is judged low (e=1), but milk transfer data are lacking.
- Is methyl morpholine oxide safe for baby skin?
- Hazard remains driven by harmonised H361f → h=2. Mechanistic evidence is lacking (m=1). Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, exposure score is increased by +1 compared with adult (adult e=1 → baby e=2) where measurable dermal absorption is plausible. No infant‑specific toxicity or exposure studies were found.
- How does VeriMom score methyl morpholine oxide?
- VeriMom scores methyl morpholine oxide at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to methyl morpholine oxide?
- See our curated list of pregnancy-safe alternatives to methyl morpholine oxide based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.