Should I Avoid dipropylene glycol dimethyl ether During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H361
Products containing dipropylene glycol dimethyl ether — check your shelf
These products list dipropylene glycol dimethyl ether on their INCI. If one is in your routine, consider swapping it during pregnancy.
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".










Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to dipropylene glycol dimethyl ether | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is dipropylene glycol dimethyl ether safe during pregnancy?
- No EU harmonised CLP classification (Annex VI) or Annex II/III restriction was found for dipropylene glycol dimethyl ether (CAS 111109-77-4); however the chemical belongs to the broader glycol‑ether/’glyme’ class for which some members have documented reproductive effects, producing a class‑based/structural alert. No peer‑reviewed developmental or fertility studies specific to this substance were located in PubMed or regulatory toxicology databases. Sources: ECHA substance/registration page, supplier SDSs, PubMed searches, EWG ingredient page.
- Is dipropylene glycol dimethyl ether safe while breastfeeding?
- Same rationale as pregnancy: no specific mammalian reproductive/developmental studies for this exact substance were identified, but the glyme/glycol‑ether chemical family includes agents with reproductive concerns (class‑based alert). No evidence was found of a demonstrated mechanism (placental transfer or lactational transfer) for this compound. Exposure from topical cosmetic use is expected to be low but measurable.
- Is dipropylene glycol dimethyl ether safe for baby skin?
- Hazard and mechanism scores follow the same class‑based concern (no direct infant data). Exposure (e) is increased by +1 for infant skin due to immature barrier and higher surface‑area‑to‑weight; the substance is a low‑to‑moderate volatility solvent with dermal exposure possible in topical products, so baby exposure judged moderate. No infant‑specific toxicity studies were found.
- How does VeriMom score dipropylene glycol dimethyl ether?
- VeriMom scores dipropylene glycol dimethyl ether at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to dipropylene glycol dimethyl ether?
- See our curated list of pregnancy-safe alternatives to dipropylene glycol dimethyl ether based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.



