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HIGH RISK

Should I Avoid cyclohexylamine During Pregnancy? | VeriMom

Cyclohexylamine (CAS 108-91-8) is listed in ECHA/CLP sources as H361f (suspected of damaging fertility) and animal studies report testicular and reproductive effects in rodents, supporting a suspected reproductive hazard rather than a confirmed human teratogen; dermal/topical exposure would be low but potentially measurable. Sources: ECHA substance/CLP listings and rodent reproductive/toxicity studies. (See sources.)

ECHA regulatory hazard statements

  • H361F

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Is cyclohexylamine safe during pregnancy?
Cyclohexylamine (CAS 108-91-8) is listed in ECHA/CLP sources as H361f (suspected of damaging fertility) and animal studies report testicular and reproductive effects in rodents, supporting a suspected reproductive hazard rather than a confirmed human teratogen; dermal/topical exposure would be low but potentially measurable. Sources: ECHA substance/CLP listings and rodent reproductive/toxicity studies. (See sources.)
Is cyclohexylamine safe while breastfeeding?
Same basis as pregnancy: harmonised/suspected reproductive classification and animal reproductive toxicity motivate a ‘‘suspected’’ hazard (h=2). Mechanistic data are limited (no clear human lactational transfer evidence), and dermal exposure from cosmetics is likely low but not negligible, so e=1.
Is cyclohexylamine safe for baby skin?
Do not increase hazard or mechanism without infant-specific evidence, so h and m remain as above. Because infant skin has higher absorption, exposure score is increased by +1 (adult e=1 → baby e=2). No infant-specific safety data were found.
How does VeriMom score cyclohexylamine?
VeriMom scores cyclohexylamine at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to cyclohexylamine?
See our curated list of pregnancy-safe alternatives to cyclohexylamine based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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