Should I Avoid butadiene During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
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Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to butadiene | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is butadiene safe during pregnancy?
- 1,3-Butadiene (CAS 106-99-0) has harmonised EU/ECHA hazard data and is classified as a carcinogen and mutagen with animal reproductive/developmental toxicity reported; mechanistic work shows reactive epoxide metabolites that are mutagenic, supporting a demonstrated mechanism relevant to reproduction/carcinogenesis (ECHA, IARC, NTP, PubMed). Topical cosmetic exposure is not a typical use form (volatile monomer/gas), so dermal exposure from cosmetics would be negligible. Sources: ECHA substance/brief profile; IARC monograph; NTP and peer-reviewed reproductive reviews (links in sources).
- Is butadiene safe while breastfeeding?
- Same hazard basis as pregnancy: harmonised classification and multiple authoritative reviews identify carcinogenicity, mutagenicity and animal reproductive/developmental effects; mechanism via reactive epoxide metabolites is demonstrated. Cosmetic/topical exposure is unlikely for the gaseous monomer so dermal absorption from cosmetic use is negligible. See sources for evidence.
- Is butadiene safe for baby skin?
- Hazard and mechanism are the same (harmonised carcinogen/mutagen, animal reproductive/developmental toxicity, reactive metabolites). 1,3-Butadiene is a volatile industrial monomer not used as a cosmetic ingredient in finished products (so dermal exposure from cosmetics is effectively negligible); therefore exposure (e) from cosmetic use to infants is scored 0. If an actual cosmetic product contained residual monomer (extremely unlikely), infant exposure and absorption concerns would be higher. See sources for evidence.
- How does VeriMom score butadiene?
- VeriMom scores butadiene at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to butadiene?
- See our curated list of pregnancy-safe alternatives to butadiene based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.