Dois-je éviter azadirachta indica seed extract pendant la grossesse ? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

azadirachta indica seed extract est-il sûr pendant la grossesse ?

Harmonised/regulatory and animal data justify a 'suspected' reproductive hazard. ECHA documentation and regulatory discussion identify margosa (Azadirachta indica) kernel/seed extracts with harmonised H361 (suspected of damaging fertility or the unborn child) for specific extracts prepared from kernels with aqueous + organic solvent processing. Multiple animal studies and reviews report antifertility, abortifacient and fetal/developmental effects (neonatal/fetal malformations, reduced fetal weight) associated with neem seed oil/azadirachtin in rodents, and mechanistic data include progesterone reduction and immune-mediated effects. For topical cosmetic use, dermal absorption is expected to be low but not zero, so exposure is scored as low but measurable. (ECHA CLH/Annex VI; animal/peer-reviewed studies).

azadirachta indica seed extract est-il sûr pendant l'allaitement ?

Same overall hazard/ mechanism as pregnancy: harmonised H361 for certain margosa/kernel extracts and animal evidence for reproductive effects from seed-derived neem preparations make this a suspected hazard for lactating people. There are no robust human lactation transfer data for cosmetic topical use; because systemic absorption from topical use is generally low but possible, exposure is scored low but measurable. Animal data indicate systemic effects after oral dosing of seed/seed-oil preparations (supporting potential for systemic exposure when dose or formulation allows).

azadirachta indica seed extract est-il sûr pour la peau de bébé ?

Hazard and mechanism remain 'suspected' based on the same harmonised/regulatory classification and animal data tied to seed/kernel extracts. Exposure score is increased by +1 for infant skin (0–3 yr) because infant skin barrier/SA:body-weight considerations raise systemic uptake potential for topically applied ingredients that have any measurable absorption in adults; there are no infant-specific dermal toxicokinetic studies for cosmetic seed extracts. Apply caution for products intended for infants if the formulation contains seed/kernel-derived neem extracts.

Comment VeriMom évalue-t-il azadirachta indica seed extract ?

VeriMom évalue azadirachta indica seed extract à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.

Quelles sont les alternatives sûres à azadirachta indica seed extract pendant la grossesse ?

Consultez notre liste d'alternatives sûres à azadirachta indica seed extract basée sur une fonction similaire et une classification sans risques connus.