VeriMomShould I Avoid acrylonitrile During Pregnancy? | VeriMom
Acrylonitrile carries harmonised CLP flags for reproductive toxicity (H361) per ECHA’s substance profile, which makes it a suspected reproductive hazard (h=2). Animal and mechanistic studies and weight-of-evidence reviews report developmental/reproductive findings and genotoxicity consistent with a demonstrated (but not fully elucidated, non-human) mechanism (m=2). For cosmetic topical use exposure is effectively negligible because acrylonitrile is not an approved cosmetic ingredient and is listed in regulatory contexts restricting use, so consumer topical exposure from intentionally formulated cosmetics is expected to be negligible (e=0).
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Is acrylonitrile safe during pregnancy?
- Acrylonitrile carries harmonised CLP flags for reproductive toxicity (H361) per ECHA’s substance profile, which makes it a suspected reproductive hazard (h=2). Animal and mechanistic studies and weight-of-evidence reviews report developmental/reproductive findings and genotoxicity consistent with a demonstrated (but not fully elucidated, non-human) mechanism (m=2). For cosmetic topical use exposure is effectively negligible because acrylonitrile is not an approved cosmetic ingredient and is listed in regulatory contexts restricting use, so consumer topical exposure from intentionally formulated cosmetics is expected to be negligible (e=0).
- Is acrylonitrile safe while breastfeeding?
- Same basis as pregnancy: harmonised/suspected reproductive classification (H361) and animal/experimental evidence indicate possible effects relevant to breastfeeding (h=2) with demonstrated mechanistic concerns in toxicology literature (m=2). Exposure from cosmetic topical products is negligible because it is not a permitted cosmetic ingredient in regulated markets and would not be intentionally present (e=0).
- Is acrylonitrile safe for baby skin?
- Hazard and mechanistic scoring mirror pregnancy/breastfeeding because the substance is suspected for reproductive/developmental effects (H361) and has animal/experimental evidence (h=2, m=2). Adult topical cosmetic exposure is expected to be negligible (no allowed use), so infant dermal exposure from cosmetics is likewise negligible (e=0); therefore no infant-specific exposure increment was applied. If acrylonitrile were present in a product used on infant skin, concern would be elevated due to its toxicity and infants’ greater vulnerability.
- How does VeriMom score acrylonitrile?
- VeriMom scores acrylonitrile at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to acrylonitrile?
- See our curated list of pregnancy-safe alternatives to acrylonitrile based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.