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HIGH RISK

Dois-je éviter acetanilid pendant la grossesse ? | VeriMom

Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

acetanilid est-il sûr pendant la grossesse ?
Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.
acetanilid est-il sûr pendant l'allaitement ?
Same animal evidence that supports a suspected reproductive/developmental hazard applies to lactation context (no human breastfeeding-specific safety data). Mechanistic concerns are theoretical (metabolism to aniline); topical absorption is likely low but measurable so maternal systemic exposure from cosmetics could be low but not zero, with potential for transfer into milk not well studied.
acetanilid est-il sûr pour la peau de bébé ?
Hazard scoring follows the animal evidence (suspected reproductive/developmental hazard). Mechanistic evidence remains theoretical. Exposure score increased by +1 for infants (per instructions) because baby skin has higher surface-area-to-weight and an immature barrier and acetanilide has measurable (though limited) dermal absorption; thus infant exposure from topical products is moderate rather than low.
Comment VeriMom évalue-t-il acetanilid ?
VeriMom évalue acetanilid à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
Quelles sont les alternatives sûres à acetanilid pendant la grossesse ?
Consultez notre liste d'alternatives sûres à acetanilid basée sur une fonction similaire et une classification sans risques connus.

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Avis Médical

Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.

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